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Cannabinoids

THC, CBD, and Beyond: Cannabinoids Explained

Understanding the molecules that make cannabis work — from THC and CBD to lesser-known cannabinoids like CBN and CBG.

By WeedCentral Editorial · 4 min read · Reviewed 2026-Q2

The Endocannabinoid System

Your body has a built-in system called the endocannabinoid system (ECS) with receptors throughout the brain and body. Your body naturally produces its own cannabinoids (endocannabinoids) that bind to these receptors. Plant cannabinoids from cannabis interact with this same system.

THC (Tetrahydrocannabinol)

THC is the primary psychoactive compound — it's what makes you feel "high." It binds to CB1 receptors in the brain, producing euphoria, altered perception, increased appetite, and pain relief. Typical flower ranges from 15-30% THC.

CBD (Cannabidiol)

CBD is non-intoxicating — it won't get you high. It's valued for anti-anxiety, anti-inflammatory, and pain-relieving properties. CBD can also moderate THC's effects, potentially reducing anxiety and paranoia. High-CBD strains are popular for daytime use.

CBN (Cannabinol)

CBN forms as THC ages and oxidizes. It's mildly psychoactive and associated with sedation. Old cannabis that's been sitting for a while tends to be higher in CBN, which is why it may make you sleepier.

CBG (Cannabigerol)

CBG is the "parent" cannabinoid — both THC and CBD start as CBG before the plant converts them. CBG itself is non-intoxicating and is being studied for anti-inflammatory, antibacterial, and neuroprotective properties.

The THC:CBD Ratio

The ratio of THC to CBD is often more important than the absolute THC percentage. A 1:1 THC:CBD strain provides balanced effects with less intense psychoactivity. A 20:1 THC:CBD strain will be strongly psychoactive. Beginners often do well starting with balanced or CBD-dominant strains.

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